Welcome to our article dedicated to the best fat burners. Let’s face it, who wouldn’t want a magic pill to lose weight? And not just for aesthetic reasons, we all know today that overweight and obesity are a real health threat, increasing the chances of suffering from numerous diseases.

Before starting with our guide, we want to make a premise immediately: there are no miraculous remedies, so we will not try to make you have false expectations.

However, there are fat burners, which are exciting compounds that can help you in the crusade against weight loss, if you use them with caution.

Here we had selected the best gnc fat burners for you that are listed below. These can be helpful in your weight loss.

GNC Total Lean Burn 60, Twin Pack, 60 Tablets per Bottle, Thermogenic to Help Reduce Calorie Intake
  • BE TOTALLY YOU: Made with a clinically-studied, cinnamon-flavored thermogenic that increases calorie burning up to 60% when used in conjunction with exercise
  • SHARP SUPPORT: Enhances mental focus
  • FEEL THE BURN: Promotes energy and metabolism
  • TWO MONTH SUPPLY: Twin pack provides a convenient back up when you need it
  • EXPERTLY FORMULATED: No artificial flavors, no preservatives, sodium free, no wheat, gluten free, no soy, no dairy
GNC Total Lean Burn & Define Vitapak
  • Multivitamin: a premium formula that helps fill in the nutrition gaps with vitamins and minerals and key nutrients that may be missing from your diet.*
  • Burn 60: a clinically researched thermogenic that boosts energy and metabolism as it increases calorie burning by up to 60%^*
  • L-Carnitine 1000: one of the most clinically studied forms of L-Carnitine available – shown to fuel fat metabolism and reduce oxidative stress post-exercise.* CLA: Conjugated Linoleic Acid, a naturally occurring fatty acid that fuels fat
  • Waterex: featuring an all-natural herbal blend, this scientific formulation helps regulate excess water.*
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GNC Total Lean CLA, 180 Softgels, Supports Exercise and Muscle Recovery
  • Because We Can't Produce Cla, We Can Only Get It Through Our Diet Or Supplements and There Are Plenty Of Benefits We Are Missing Out On. Gnc Total Lean Cla Is Scientifically Shown To Improve Body Composition, Improve Lean Muscle ToneAnd Fuel Energy And Fat Metabolism Without Stimulants.Gnc Total Lean Products Were Created To Help You Take Control Of Your Weight Loss Goals, Focus On Your Health And Still Be Totally You. Benefits: Contains 2000Mg Of
  • Improves Body Composition
  • Improves Lean Muscle Tone
  • Fuels Energy And Fat Metabolism Without Stimulants
  • Gluten Free
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Burn-XT Thermogenic Fat Burner - Weight Loss Supplement, Appetite Suppressant, & Energy Booster - Premium Fat Burning Acetyl L-Carnitine, Green Tea Extract, & More - 60 Natural Veggie Diet Pills
  • Support healthy weight Loss: Burn xt is a thermogenic fat burner supplement for men and women. Each capsule contains natural, powerful thermo fat-burning ingredients. The synergistic formula helps burn fat, increase energy, preserve lean muscle, suppress appetite, and boost metabolism.*
  • Energy booster & appetite suppressant: Help keep food cravings in check and your diet on track with these safe and effective fat burning pills. Improve energy levels - use in the morning or pre workout. Support fast fat loss with keto friendly energy to help burn fat and lose weight.*
  • No artificial fillers: Burn xt was created with absolutely no fillers. Burn Xt works differently by targeting multiple fat burning processes in the body.*
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GNC AMP Men's Ripped Vitapak Program, 30 Packs, with Metabolism and Muscle Support
  • GNC AMP Men's Vitapak delivers the power of four science-based formulas to help you achieve your daily nutritional goals as you strive for a lean, sculpted physique^
  • Clinically studied men's multivitamin blend shown to work better than a basic multivitamin and packed with antioxidants to help fight free radicals that can be produced from your workout
  • Thermo blend clinically shown to increase metabolism before, during and after exercise; plus burn up to 12x more calories
  • In a randomized, double-blind, placebo-controlled study of 112 healthy volunteers, subjects taking GNC vitamin and mineral blends for six weeks experienced significant improvements in certain nutrients and key SF-36 health questionnaire scores compared to a placebo
  • In a double-blind, randomized, placebo-controlled, cross-over study, 25 subjects exercised on a treadmill on two occasions. On one occasion, the subjects took the thermogenic blend before exercise and on the second occasion, they took a placebo. When the subjects took the thermogenic blend, they burned three times more calories before, 3% more calories during and 12 times more calories after exercise compared to when they took the placebo
GNC Total Lean Appetrex Control, 60 Tablets, Reduces Calorie Intake
  • You're Committed To Looking And Feeling Your Best, But Sometimes You Need A Little Help;We're Committed To Helping You Get There. Appetrex Control? Is A Dietary Supplement That Provides Clinically Studied Results You Can Count On. Gnc Total Lean Products Were Created To Help You Take Control Of Your Weight Loss Goals, Focus On Your Health And Still Be Totally You. Benefits: Shown To Reduce Calorie Intake^
  • Fuels Energy &Metabolism
  • Enhances Mental Focus
  • ^In A Clinical Study Of 30 Healthy Adults (Who Took Appetrex Control? One Week Followed By A Placebo One Week Apart, Or Vice Versa), Calorie Intake Was Reduced By Nearly 10% When The Subjects Took Appetrex Control? Versus The Placebo Prior To Their First Meal At The Start Of Their Diet.
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GNC Total Lean Thermo CLA, 90 Softgel Capsules, Supports Exercise and Muscle Recovery
  • GNC Total Lean Thermo CLA Is A Potent, Energizing FormulaWith Many Benefits To Assist You Throughout Your Weight Loss Journey. Your Body Is Working Hard At The Gym, So Give It The Attention It Needs With Thermo CLA's Exercise And Muscle Recovery Support.Gnc Total Lean Products Were Created To Help You Take Control Of Your Weight Loss Goals, Focus On Your Health And Still Be Totally You. Benefits: Contains 1500Mg Of Cla Per Serving, Which Fuels Energy A
  • Scientifically Formulated To Be A Potent, Energizing Formula
  • Supports Exercise And Muscle Recovery
  • Supports Exercise And Muscle Recovery
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GNC Mega Men Energy Metabolism 90 Caplets
  • GNC Mega Men Energy & Metabolism 90 Caplets - New Formula
GNC Total Lean CLA + Carnitine - Orange Sorbet, 60 Servings, Supports Muscle Recovery
  • GNC Total Lean Cla + Carnitine Is Scientifically Formulated To Help You Reach Your Goals. Enjoy The Delicious, Naturally Flavored Orange Sorbet Taste Without Compromising Your Journey. Gnc Total Lean Products Were Created To Help You Take Control Of Your Weight Loss Goals, Focus On Your Health And Still Be Totally You. Benefits: 1.7G Of Cla And 1 G Of L-Carnitine Per Scoop
  • Helps To Improve Body Composition and Fuel Muscle Recovery
  • Facilitates The Metabolism Of Long-Chain Fatty Acids And To Help With The Transport Of Long-Chain Fatty Acids
  • Stimulant Free And Sugar Free
CHALLENGE by GNC CHALLENGE By GNC Pre-Workout Intensity, Ultra Punch, 15.9 Ounce
  • Ultra-Concentrated & High Energy
  • Explosive Energy & Focus
  • Blood Flow & Muscle Pumps
  • Performance & Alertness
  • 200mg Caffeine, 1.6g Beta-Alanine, 3.75g Pump Matrix, 2.5g Creatine

Buyer Guide to Choose Gnc Fat Burners

Fat burners are a very different series of products that promise to improve body composition by eliminating stored fat or preventing the creation of new deposits. Their effects on metabolism are not yet well known, so it is necessary to act wisely during supplementation.

What Are Fat Burners and How Do They Work?

Fat burners are supplements or food supplements that are used to stimulate body weight loss. In general, this effect is achieved through an increase in energy expenditure, which will require greater destruction of the stored lipids to produce energy.

They have a different mechanism of action than thermogenic fat burners and will be discussed in another article in more detail. There are countless supplements called fat burners. Their operation is not yet well known and still presents unknowns to experts.

Are Fat Burners Safe?

Freely sold fat burner supplements are not subject to the same health standards as medications, so consumers should act very carefully when purchasing a new weight loss product.

Most of these side effects can be prevented by avoiding exceeding the recommended daily dose and refraining from combining fat-burning molecules or with other compounds, such as alcohol, drugs, or medications.

However, the potential danger posed by the following fat burners makes the options undesirable in any case:

  • Capsaicin. Capsaicin is the active compound of hot peppers. In food, this molecule is found in minimal concentrations and is harmless. However, the administration of large quantities of this substance could favor the appearance of tumors and long-term neurological damage.
  • Raspberry Ketones. This compound has become very popular in herbalists and nutrition stores, taking pride of place among fat burning supplements. However, the absence of reliable studies on its long-term safety and its potential cardiotoxic effect makes it an undesirable option.
  • Chrome Salts. Depending on their formulation, chromium salts can act as oxidizing molecules harmful to the body’s tissues. Chromium nicotinate is considered a safer option; however, more studies are needed before the safety of this compound can be clarified.
  • Synephrine. Synephrine is made from bitter orange extract. Despite its natural origin, this molecule is a powerful activator of the sympathetic nervous system (responsible for our body’s fight and flight reactions), which can cause dangerous tachycardias and increases in blood pressure.

After discarding the most insecure compounds, we continued to analyze the composition of other supplements with a fat-burning activity, which, without being toxic, can become dangerous under certain conditions.

The following supplements, therefore, require informed use and must be analyzed in individual articles :

  1. Conjugated Linoleic Acid (CLA). Although CLA has proven to be a harmless compound in animal experiments, it has been shown that it has the potential to damage the liver of healthy people if the maximum recommended dose (3 g) is exceeded or if it is used for some time longer than six months.
  2. Garcinia Cambogia. This plant-based supplement has been used safely for years, even at high doses. However, its use in combination with other fat burners or certain medications may be toxic. For this reason, it must be analyzed more carefully.
  3. Green Tea. Although tea is considered safe in the infusion and accompanied by food, cases of liver damage have been reported following the consumption of poor quality green tea supplements (containing heavy metals or other contaminants), therefore a thorough examination of each product before starting with an integration.

Therefore, after careful investigation, we have removed seven of the fifteen most popular fat burners from our list.

The side effects of green coffee, caffeine, forskolin, fucoxanthin, L-carnitine, ginseng, taurine, and yohimbine are mild enough to be used with relative safety. But what about its effectiveness?

Are Fat Burners Effective?

It is useless to find a reliable and easy-to-use fat burning supplement if its effects are not satisfactory. In the following lines, you will find a summary of the latest information on fat burners that have passed our safety criteria, with references to the most recent studies:

  1. Chlorogenic acid (green coffee) – Chlorogenic acid is a polyphenol with antioxidant and anti-inflammatory activity. In animals, this compound can reduce the fatty tissue accumulated in the body, contributing to weight loss. However, it has not been established whether this fat loss results in tangible results in humans.
  2. Caffeine – The activating effect of caffeine has been shown to accelerate the body’s metabolism in the short term. In the long run, however, tolerance to the results of this molecule is produced, and its fat-burning effect is lost.
  3. Forskolin – Forskolin is a compound found in a mint-related plant (Coleus forskohlii). In the form of supplements, forskolin has proven useful in reducing the fat mass of obese rats. Even in a study with overweight men, this product was able to achieve significant weight loss.
  4. Fucoxanthin – Fucoxanthin is obtained from seaweed Undaria pinnatifida. Human studies have shown that this compound can promote weight loss and oxidation of fat mass in humans, although the clinical studies available so far may be subject to various conflicts of interest.
  5. L-Carnitine – L-carnitine acts as a fat transporter to the mitochondria (responsible for body energy production); therefore, it is essential to maintain adequate levels of this substance to use lipids as fuel. Its effectiveness decreases in people who already have sufficient carnitine levels.
  6. Panax Ginseng – The root extract of this millennial plant has high fat-burning power in studies on obese rats. Human studies show that ginseng supplementation has a slight slimming effect, which combines with other benefits (such as a strengthening of the intestinal microbiota).
  7. Taurine – A cyclist supplement was given to professional cyclists in a 2010 study, hoping to find an increase in their physical performance. Although no improvement in the athletic parameters of these subjects was found, a significant increase in fat oxidation was observed.
  8. Yohimbine – There are two studies (conducted respectively in 1991 and 2002), relating to yohimbine (from the bark of the African tree Pausinystalia Yohimbe), which demonstrate an increase in weight loss in the elderly on a low-calorie diet. Unfortunately, this effect was not reproduced in subsequent experiments.

Most fat burners are capable of promoting weight loss in animals. However, human experiments have been conducted on a small number of individuals who need further studies before they can ratify their effects.

Caffeine is the exception, being unequivocally capable of speeding up the metabolism (for a short period).

How to Take a Fat Burner to Get the Most Out Of It?

It is necessary to demonstrate that the effects of fat burners depend, to a greater or lesser extent, on the degree of physical activity.

The best way to increase basal metabolic expenditure (amount of calories consumed by our body at rest) is through sport. They will not be useful in combination with a sedentary lifestyle.

Also, a series of healthy lifestyles will help increase the chances of success of our fat burning supplement, avoiding the appearance of the dreaded “rebound effect” (recovery of the weight lost when the use of the fat-burning product is abandoned). You will find them described in the following list:

  • Follow a healthy diet. A diet low in simple carbohydrates (but which provides enough protein, good fats, vitamins, and minerals) will contribute to weight loss. Also, reducing the intake of ‘bad’ fats prevents the onset of gastrointestinal adverse effects from supplements such as forskolin.
  • Drink. The most stimulating fat burners, such as caffeine, cause an increase in body temperature and sweating. The contribution of water (also in the form of soups, infusions, or drinks) will be significant to avoid the appearance of dehydration.
  • Get enough rest. People who sleep less than 7-8 hours each night are more likely to suffer from obesity, diabetes, and hypertension. If you want to get the most out of your fat burner, keep your metabolism healthy while respecting the hours of rest.
  • Stay away from alcohol and drugs. Since many fat burning supplements require liver function metabolism, it is not recommended to combine them with alcohol, which also depends on this organ for proper elimination. Some exciting drugs, such as amphetamines, could potentiate the effects of fat burners with potentially lethal consequences.

What Precautions Should I Take While Taking a Fat Burner?

Supplementation with a fat burner should be considered fundamentally different from that performed with any other food supplement.

The use of a fat burner should be limited in time (until the desired amount of weight is lost), and its use is not recommended for people with weight within the expected parameters.

Can I use fat burners if I suffer from chronic conditions? People with cardiac, hypertensive, diabetic, renal, metabolic, neurological, psychiatric, or muscular conditions should refrain from using fat burners without the prior approval of a doctor.

Can my drugs interact with fat burners? Surely! Unfortunately, fat burners can affect drugs, decrease their effects, or generate dangerous reactions. Although each of these products can interact with different medications, the main substances involved will be:

  1. Anticoagulants
  2. Antidiabetic
  3. Psychiatric Drugs
  4. Antihypertensive
  5. Antithyroid
  6. Thyroid Hormones
  7. Contraceptives

Can children take fat burners? The safety of fat burning supplements in children who have such a vulnerable metabolism has not been studied. For this reason, it is recommended not to administer fat burning supplements under the age of 18.

What about pregnant or breastfeeding women? The influence of fat burners on the fetus or their presence in breast milk has not been studied, although there is evidence that these supplements could adversely affect the growth of the baby. Therefore, its use is not recommended.

In conclusion, the people who can make safer use of fat burning supplements will be those who are healthy, in good general condition, and who do not take drugs for chronic diseases. Otherwise, it is advisable to consult a doctor before starting to use a new fat burner.

Purchase Criteria

The real challenge of fat burners is that of deciding when to buy them. You won’t find hundreds, but thousands of items that will promise you to “dissolve” unwanted fat from your body at a meager price.

Don’t be fooled by empty promises and read our purchase criteria before entrusting your health to an unknown manufacturer.

  • Dietary needs
  • Origin of the product
  • Sensitivity to stimulants
  • Combination of ingredients
  • Preservation and expiration

Dietary Needs

Don’t lose sight of your dietary preferences, allergies, and intolerances. If you are celiac, make sure your fat burning product is labeled “gluten-free.”

If you are vegan, take a plant-based supplement, for example, based on ginseng or caffeine. Pay attention to the capsules of these supplements, which can be made of animal jelly.

Origin of The Product

Intoxication has been described during integration with forskolin and fucoxanthin secondary to the contaminating products contained in these articles.

It is essential to avoid any type of toxic or pesticide in our fat burners; choose organic farm products whenever you are looking for a plant extract.

Sensitivity to Stimulants

Pay close attention to stimulant-based supplements, such as ginseng or caffeine. If you are a nervous or anxious person, these fat burners can worsen your condition and give you a very unpleasant experience.

Know yourself, and if your personality is prone to discomfort, opt for other compounds, such as fucoxanthin.

It should be noted that while caffeine is considered quite safe in the recommended doses, its overdose can cause arrhythmias, hypertension, and even brain edema and death.

Caffeine sensitive people can present this syndrome using standard doses, so they should refrain from using any fat burners with caffeine.

Combination of Ingredients

Remember that most of the side effects of fat burners (usually a fulminant liver failure, kidney failure, or cardiovascular disease) have appeared after using supplements containing various combinations of fat-burning elements.

For safety, choose a supplement based on a single product and avoid mixing it with other ingredients.

Preservation and Expiration

Follow the Manufacturer’s instructions for storing the fat burning product. In general, these items should be kept in a cool, dry place away from sunlight.

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